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(TERJEMAHAN) Tajuk: Madu asli merendahkan glukos plasma, protin C-reaktif, homosistin, dan lipid darah di dalam subjek sihat, diabetik dan hiperlipidemik: perbandingan dengan dekstros dan sukros.


The Science Behind Apitherapy


Raw Honey


Title: Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucrose.


Author: Ai- Waili NS Journal: J. Med Food. 2004 Spring (1):100-7.


*** with Dr.Weeks’ and Dr. Yusof comments****


This study included the following experiments:


i.effects of dextrose solution (250ml of water containing 75g of dextrose) or honey solution (250 ml of water containing 75g of natural honey) on plasma glucose level (PGL),plasma insulin, and plasma C- peptide (eight subjects):


ii.effects of dextrose, honey, or artificial honey (250 ml of water containing 35g of dextrose and 40g of fructose) on cholesterol and uriglycerides (TG) (nine subjects):


iii.effects of honey solution, administered for 15 days on PGL, blood lipids, C-reactive protein (CRP). And homocysteine (eight subjects);


iv.effects of honey or artificial honey on cholesterol and TG in six patients with hypercholesterolemia and five patients with hypertriglyceridemia:


v.effects of honey for 15 days on blood lipid and CRP in five patients with type 2 diabetic mellitus; and


vi.effects of 30g of sucrose or 30 g of honey on PGL, plasma insulin and C-peptide in five diabetic patients.




In healthy subjects:


      Dextrose elevated PGL 52% at 1 and 3% at 2 hours, and decreased PGL 20% after 3 hours.

      Honey elevated PGL 14% after 1 hour and decreased it 10% after 3 hours.

      Elevation of insulin and C-peptide was significantly higher after dextrose than after honey.

      Dextrose and artificial honey both reduced cholesterol and low-density lipoprotein-cholesterol (LDL-C) and increased TG. Honey also reduced cholesterol and LDL-C; however it reduced TG and slightly elevated high-density lipoprotein-cholesterol (HDL-C) .

      Honey consumed for 15 days decreased cholesterol (7%),LDL-C (1%), TG (2%), CRP (7%), homocysteine (6%), and increased HDL-C (2%).


In patients with hyper-triglyceridemid:


      Artificial honey increased TG, while honey decreased TG.


In patients with hyperlipidemia:


      Artificial honey increased TG, while honey decreased LDL-C.


In diabetic patients:


      Honey decreased cholesterol (8%), LDL-C (11%), and CRP (75%) after 15 days.

      Honey compared with dextrose caused a significantly lower rise of PGL.

      Elevation of PGL was greater after honey than after sucrose at 30 minutes, but was lower at 60, 120 and 180 minutes.

      Honey caused greater elevation of insulin than sucrose did after 30,120, and 180 minutes.


Conclusions of the authors were that:


      Honey reduces blood lipids, homocysteine and C-reactive protien(CRP) in normal and hyperlipidemic subjects.

      Honey caused lower elevation of plasma glucose levels (PGL) in diabetics compared to dextrose and sucrose.



Dr. Weeks’ comments:


Here we have a well-designed study that delights us in its counter-intuitive conclusion; honey does help treat diabetic! Not surprisingly, other sweeteners did not show any healthy benefits. For example, dextrose in water, artificial "honey" (dextrose and fructose), and sucrose (while sugar) caused harm. But raw honey, the good stuff .lowered blood sugar as well as lowering risk factors for heart disease (total cholesterol, "bad" LDL cholesterol, homocysteine, and the inflammatory marker C-reactive protein). Honey

also raised the "good" HDL cholesterol. So sweeten with raw honey and stop all that artificial stuff that increases so many health risks.


Years ago, Charlie Mraz knew that diabetics could eat raw honey and have no problems. He explained that raw homey, a peptide-rich living food, was a complex carbohydrate that needed enzymatic processing in the liver (by an invertase enzyme) in order to metabolize the honey into bio-available simple sugars of sucrose and fructose. This is a "slow-burning" sugar, a stick-to-your-ribs enzyme-rich food that does not strain the pancreas (does no harm) while at the same time delivering nutrients and amino acids.


BONUS: Aside from eating this wonderful gift of the bees. I use honey in my clinic for a variety of other purposes. I have used successfully topically for acceleration of wound repair (suture, bedsores, burns, ulcers); as an antibiotic (pinkeye, infected wounds): as a skin treatment for acne and youthful glowing skin (honey is both an alpha- and a beta- hydroxyl acid for mild peeling and detergent effects) and most impressively intranasally to unclog sinuses and to create the wave of death to this resident bacteria and viruses that cause sore throats. As the wave of raw honey runs down the nostrils and becomes a sweet post-nasal drip. It disinfects and rejuvenated the nasal pharyngeal tissue. Yes, IT STINGS (to the degree that your tissue is inflamed), but in my 20 years of practice I have never seen anything help sore throats like raw honey (which contains glucose peroxide).


Bradford S. Weeks, M.D., science editor and past president and founding member of the American Apitherapy society, has a passion to bring the benefits of apitherapy out of the hive and into the home so as remind people of the safe and effective qualities of these ancient folk remedies. He offers a regular column describing the scientific rationale for various aspects of apitherapy. For more information see and direct questions to Bee Well!!




Kajian yang di jalankan jelas menunjukan madu dapat mengawal paras gula untuk pesakit kencing dan mengawal paras kolesterol. Walaupun kajian makmal ini dapat membantu anda yang terlibat secara langsung dengan madu untuk membuat penerangan khasiat madu terhadap sakit kencing manis dan tinggi paras kolesterol, adalah di nasihatkan agar anda TIDAK terus menyatakan madu penawar kepada sakit kencing manis, pengalaman saya pesakit kencing manis dan darah tinggi yang mengamalkan madu,saya nasihatkan terus makan ubat-ubat dari klinik. Alhamdulillah , ada antara mereka telah mula mengurangkan dos ubat dan paras gula masih dapat dikawal, malah mereka lebih bertenaga. Sekiranya anda masih musykil dan ingin penerangan lanjut dengan jurnal ini, sila email kepada saya: